mspipeline

This list gives a bit more detail about the phase 1 trials in progress. Typically, if there is an announcement of a drug successfully completing a trial, I will move it to the next stage before I see a press release or report saying that a new trial is starting. I assume it will move to the next stage.

[updated November 24, 2009]

Phase I Trials

1. Amiloride (0xford University)

http://news.bbc.co.uk/2/hi/health/7086911.stm

2. AZD5904 (AstraZeneca)

http://www.astrazeneca.com/_mshost3690701/content/resources/media/investors/AZN-Q2-2009/AZN-Q2-2009-Pipeline.pdf

3. BaroFeron (BaroFold)

http://www.barofold.com/73/BaroFeron/

4. CCX140 (CCR2 antagonist) (ChemoCentryx)

http://www.chemocentryx.com/product/CCR2.html

http://www.chemocentryx.com/product/overview.html

5. CS-0777 (Daiichi-Sankyo)

http://clinicaltrials.gov/show/NCT00616733

6. Extracorporeal photochemotherapy (University of Milano-Bicocca)

http://www.springerlink.com/content/a3722uqnq355n4n4/

7. Far Infrared Irradiation (GAAD Medical Research Institute, Canada)

http://www.clinicaltrials.gov/ct2/show/NCT00674934

8. GRC 4039 (Glenmark Pharmaceuticals)

http://www.glenmarkpharma.com/research/clinical.html

9. INCB8696 (Incyte)

http://www.incyte.com/drugs_product_pipeline.html

10. Linoleic Acid (omega-6) (University of Rochester)

http://www.clinicaltrials.gov/ct2/show/NCT00638196

11. Lipoic acid (Oregon Health and Science University)

http://www.ohsu.edu/xd/research/centers-institutes/neurology/multiple-sclerosis-center/research/index.cfm

http://www.clinicaltrials.gov/ct2/show/NCT00676156

http://www.researchcrossroads.org/index.php?view=article&id=50%3Agrant-details&option=com_content&Itemid=64&grant_id=3794469

12. Low Fat Diet (Oregon Health and Science University)

http://www.clinicaltrials.gov/ct2/show/NCT00852722

13. Mesenchymal stem cell transplantation (autologous) (Cleveland Clinic)

http://www.clinicaltrials.gov/ct2/show/NCT00813969

14. MLN0415 (Millenium / Sanofi-Aventis)

http://www.mlnm.com/rd/inflammation/candidates/mln0415.asp

15. MM-093 (Recombinant Human Alpha-Fetoprotein) (Merrimack)

http://www.merrimackpharma.com/pipeline/index.html

16. NI-0401 (NovImmune)

http://www.novimmune.com/press/com20060626.php

17. ONO-4641 (oral S1P receptor agonist) (Ono Pharmaceutical)

http://www.ono.co.jp/jp/ir_info/annual/pdf/2008/fi0804.pdf

18. Prolactin (Stem Cell Therapeutics / U of Calgary)

http://www.stemcellnetwork.ca/projects.php

http://www.stemcellthera.com/pdf/SCT3Q08MD_A.pdf

http://cnrp.marketwire.com/cnrp_files/20080707-707sss.pdf

http://cnrp.marketwire.com/cnrp_files/20090409-409SSS1.pdf

19. R1295 (Roche)

http://www.roche.com/research_and_development/pipeline/roche_pharma_pipeline.htm

20. SC12267 (4SC AG)

http://www.4sc.de/en/index.php?csrc=http://www.4sc.de/en/news/releases/07_04_26_eng_Studienhalbzeit.htm

http://www.dvcg.de/gb/news/portfolio_presse.asp?artikel=504

21. Sildenafil Citrate (aka Viagra)

http://clinicaltrials.gov/ct/show/NCT00094068

22. TBC-4746 (Encysive Pharmaceuticals / Pfizer)

http://www.encysive.com/products.html

23. TK54 (LTKfarma)

http://www.genopole.org/media/pdf/eng/annuaire/entreprises/ltk-farma-en.pdf

http://www.prnewswire.co.uk/cgi/news/release?id=174816

24. Valomaciclovir (EPB-348) (Epiphany Biosciences)

http://www.epiphanybio.com/news/Press_Release_23MAR09.pdf

http://www.epiphanybio.com/pipe/index.html