Archive for March, 2008

FYAK

Based on this article, I added FYAK to phase 1.

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Osteopontin

I removed Osteopontin (aka TACI-Ig) (Merck Serono and ZymoGenetics) from phase 1 as it is no longer listed in Merck Serono’s pipeline.

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AVE9897

I removed AVE9897 (Sanofi-Aventis) from phase 1 as the drug is no longer listed in the company’s pipeline.

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Helminths

I moved helminth induced immunomodulation from pre-clinical to phase 1 based on this article.

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BGC20-0134

I added BGC20-0134 from BTG to the phase 1 list based on this article.

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TBC-4746

I’m adding TBC-4746 from Encysive Pharmaceuticals to the phase 1 list. The company is in the process of being bought out by Pfizer. The drug is a VLA-4 antagonist, like tysabri, but is taken orally.

http://www.encysive.com/clinical.html

http://www.encysive.com/products.html

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Topiramate with Avonex

I removed “Topiramate (aka Topamax) (with Avonex)” from the phase 2 list as I can’t find any information that shows it is still going.

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