Comments for mspipeline

Comment on Full List by Geoff

Geoff — Fri, 20 Nov 2009 06:27:46 +0000

Janet,
I take rebif and I just got my H1N1 and seasonal flu vaccines today. I based it on this info from the Canadian MS society:

http://www.mssociety.ca/en/flu_h1n1_vacc.htm

I got the version without adjuvant.

Geoff

Comment on Full List by Janet Summers

Janet Summers — Wed, 18 Nov 2009 10:45:40 +0000

Thanks for keeping us up to date, but do you have any news as to whether we should take the new vaccine for Swine flu? I am on avonex, and can’t decide what to do.

Comment on Full List by Kreso

Kreso — Sat, 07 Nov 2009 22:53:14 +0000

Thank you for this list !!
You have put an optimitisc smile on my face !

Comment on Full List by AL RPH

AL RPH — Thu, 20 Aug 2009 22:10:48 +0000

I believe this article will be of interest to all.

http://www.newswise.com/articles/view/555107/

Comment on Full List by Geoff

Geoff — Sun, 09 Aug 2009 21:32:51 +0000

ddietrich, thanks for the feedback. I really hope Fampridine and nerispirdine can be of use to people with MS.

I decided not to track the symptomatic treatments in the pipeline. Tracking all of the symptomatic treatments that could be used for MS would be a big job in itself and I decided not to take it on.

Comment on Full List by ddietrich

ddietrich — Fri, 07 Aug 2009 16:29:41 +0000

The FDA is supposed to respond by April to Acorda’s submission for approval for Fampridine SR by October 2009. Another drug with a similar mechanism of action is in clinical trials for MS presently. Look at nerispirdine, under identifier NCT00811902 at clinicaltrials.gov.

Comment on Full List by Geoff

Geoff — Thu, 23 Apr 2009 01:21:20 +0000

I don’t use Google alerts. I do use Google News, clinicaltrials.gov, the US MS Society’s list of clinical trials, Pubmed, conference abstracts from the major neurology/MS conferences and last but not least, tips I get, especially at ThisIsMS.com.

Geoff

Comment on Full List by Fernando

Fernando — Wed, 22 Apr 2009 14:47:33 +0000

Ok. You’re right.

How do you keep track of everything? Do you use google alerts or something similar? Goggle alerts is a fine tool.

Fernando

Comment on Full List by Geoff

Geoff — Mon, 20 Apr 2009 21:28:18 +0000

Fernando,

Thanks for the information. I’m always glad to get tips. For a couple of reasons, I’m not going to add either drug. On BVA-101, it is preclinical, which I’ve given up tracking. I have some stats on the approval rate for drugs (in general, not MS-specific) that indicates that around 10-12% of all drugs that enter phase 1 go on to be approved one day. But of all the compounds tested in the preclinical stage, only around 10% ever even make it into clinical trials. So the odds are that around 1% of the drugs on the preclinical list will one day be treatments, and there aren’t even 100 drugs on the list…so after realizing the futility of it, I decided to give up. But I kept the preclinical section there, in case anybody is interested.

On Cethrin, it does sound interesting, and it sounds like the kind of thing that could one day be used in MS, but in trying to decide what I would include on the list and what I wouldn’t, I arbitrarily decided to include drugs that aren’t in trials for MS at the moment, but where there is a recent statement from the drug sponsor saying they intend to begin MS trials soon (or something to that effect). For Cethrin, I don’t see any reference to one day testing on people with MS. If there is a statement like that out there, let me know and I’ll add it to the list right away.

Thanks again for the info.

Geoff

Comment on Full List by Fernando

Fernando — Mon, 20 Apr 2009 19:45:56 +0000

There is a drug called BVA-101 that could fit in the pre-clinical section:

http://www.thisisms.com/ftopict-7035-bva101.html

Is there a reason for it not being in that section?

If it is so, please forget this comment.

Fernando